James Prescott on Day 2
|Portrayed by||Alan Dale|
|First appearance||Day 2: 12:00 AM – 1:00 AM|
|Last appearance||Day 3: 7:00 AM – 8:00 AM|
 Day 2
After the nuclear strike on the United States failed, Vice President James Prescott urged President Palmer to retaliate on the Middle Eastern countries believed responsible. Palmer declined because of new evidence from Jack Bauer, so Prescott invoked the 25th Amendment, declaring Palmer unfit to lead and removing him from office.
After learning that the recordings responsible for the assumptions were in fact false, and created by a man named Peter Kingsley, Prescott restored power to Palmer and offered his resignation. President Palmer refused to accept the offer though.
 Day 3
Vice President Prescott returned in Day 3 only appearing via teleconference in a cabinet briefing with President Palmer and staff regarding the Cordilla virus threat and the execution of Ryan Chappelle.